Neurotransmitter testing of brain toxins

Consequences of Increased Toxin Levels

At the 2017 IMMH conference in Los Angeles, Dr. Sponaugle presented clinical research that correlated thousands of toxin levels with changes in Neurotransmitter testing.

Our clinical research has correlated specific lipophilic toxins levels, some mold mycotoxins, and some petroleum-based toxins, with the reduction of enzyme activity.

There is an obvious inverse relationship, the higher the level of the circulating toxin, the more down-regulation of the specific enzyme activity.

Our clinical research was performed with timely and precise clinical testing.

Toxin levels and Neurotransmitter ratios were measured immediately before, and immediately after sufficient IV Glutathione was given to minimize the circulating toxin level.

The increased function of the converting enzyme occurred almost immediately following an aggressive IV infusion of Glutathione, in approximately one or two circulation times following a Glutathione.

A great example of this phenomenon is often seen when patients suffer Ochratoxin poisoning. Extremely high levels of the mycotoxin, Ochratoxin, down-regulate the function, and subsequently, the natural downstream conversion of Dopamine to Norepinephrine.

Ochratoxin floating throughout the bloodstream at significant levels will down-regulate the natural “downstream” conversion of Dopamine to Norepinephrine.

The Ochratoxin attaches to the enzyme “Dopamine Beta Hydroxylase” and prevents an efficacious conversation of Dopamine to Norepinephrine.

This phenomenon does not occur when the Ochratoxin is sequestered within the polysaccharide “glue” of the Biofilm formations spun by Lyme spirochetes and other foreign infectious agents.

I have successfully treated many Autistic children who were poisoned by Ochratoxin, usually from a basement bedroom.

While I consider optimal levels of Dopamine on Neurotransmitter testing to range from 170 to 190, these Autistic children often suffer from excessive Dopamine levels of 600 to 1000.

Dopamine levels at 800 can cause severe panic disorder, paranoia, bipolar behavior, and tachycardia.

Dopamine activates the Beta One neuron receptor on cardiac neurons and the primary cardiac pacemaker, the SA node.

Hence, significantly elevated Dopamine levels of 600 to 800 can cause severe Sinus Tachycardia and, worse, Cardiac Irritability in which all of the Atrial Neurons attempt to take over the responsibility of controlling heart rate – this can cause Atrial arrhythmias and even Atrial Fibrillation.

The longer the Autistic child can play in a basement saturated with Ochratoxin gas, the more damage their brain sustains.

The flip side of the Ochratoxin-induced shutdown of the enzyme “Dopamine Beta Hydroxylase” is that the patient suffers from severe suboptimal Norepinephrine levels.

Norepinephrine activates the Aloha One nerve receptor responsible for maintaining vascular tone, especially when the patient changes from sitting to standing.

Normal Norepinephrine levels range from 35 to 45, and the Ochratoxin-induced down-regulation of Dopamine Beta Hydroxylase leaves these patients with Norepinephrine levels as low as 4 or 5.

These patients suffer tremendous POTS issues because they have insufficient Norepinephrine to attach to the nerve receptors on the vascular blood vessels.

They suffer from a reduced venous return to the heart because the blood simply “pools” in their dependent extremities.

The resultant diminished blood flow returning to the heart is known as “cardiac filling pressure.”

Cardiac filling pressure increases the muscular squeeze of the left ventricle and, subsequently, increases cardiac output.

Through deductive reasoning, we can comprehend how severe Ochratoxin poisoning can cause a dangerous chain of events that can potentially compromise the entire cardiovascular system.

Medical Director at Sponaugle Wellness Institute | 1-877-737-1959 | Meet Dr. Sponaugle | + posts
Dr. Rick Sponaugle, MD, is a licensed medical doctor in Florida, integrative physician, and board-certified anesthesiologist. With an emphasis on Environmental Medicine, Dr. Sponaugle specializes in treating brain and neurological disorders derived from Mold Toxicity, Industrial Toxicity, Gut Toxicity, Neurological Lyme disease, and five additional stealth infections that attack the Brain and Neurological system of most patients. Our Medical Director, Rick Sponaugle, MD, is an integrative physician who attempts to prioritize treatment through quality forensic medicine. Performing an analysis of 400 numerical bio-markers in his initial consultation, Dr. Sponaugle's goal is to diagnose and treat the underlying cause of your multiple symptoms.
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