Lyme Disease

Our Research Has Shown "Chronic" Lyme Disease patients suffer from a combination of Mold Toxicity and Industrial Toxicity

Holistic Lyme Disease Treatment Backed By Science & Research

Sponaugle Wellness's therapeutic approach for the treatment of Lyme Disease synergizes innovative, non-toxic protocols supported by the latest research with natural healing modalities from around the world.

Our multidisciplinary integrative medical team is specialized in methodical diagnostic and treatment procedures that trace your symptoms to the root cause, and target the Lyme spirochetes, coinfections, and toxins from your cells while tending to your most troublesome symptoms so you can live without fear of a flare and with faith, you'll get your life back.

The average Lyme patient who walks into our clinic has seen 20 or more physicians, most of whom were not Lyme Literate or misdiagnosed the patient with one of the countless diagnoses mistaken for Lyme Disease.

Our Lyme Disease treatment protocols focus on a hybrid of conventional and alternative medicine that promotes holistic healing for the patient while addressing the underlying infections and toxicities.

What is lyme disease?

If you’re like most of our patients, you already know a lot about Lyme disease. You might even be more informed than many medical doctors. Not only are you living with Lyme Disease, but you’ve spent countless hours poring over the latest Lyme disease treatment research in hopes of a breakthrough test that will validate your suffering or a novel therapy that’ll bring you relief.

Perhaps you were only recently diagnosed after months or years of debilitating pain, fatigue, weakness, or frightening neurological symptoms. You wouldn’t be alone. Over 70% of Lyme Disease patients see four or more doctors before receiving a correct Lyme diagnosis. Many are accused of exaggerating their symptoms or are referred to a mental health specialist.

Even with a confirmed case of Lyme disease, you may have been excused. Unfortunately, to the mainstream medical community, Lyme disease is simply an illness that’s successfully cured with a couple of weeks of antibiotics. It’s an open-and-shut case in the minds of most physicians.

Serving as the last chance Lyme treatment center in Oldsmar, Florida, our practitioners recognize no two Lyme disease patients are the same. We respect every aspect of the journey you've taken to arrive at our doors and acknowledge you as an equal partner in care. We’re dedicated to unraveling the complexity of the most progressive Lyme disease cases, providing personalized care that takes your whole self into consideration...body, mind, and spirit.

Lyme disease treatment in florida
Florida Lyme Disease Clinic
What is lyme disease?

Ben's story of healing from lyme disease and mold toxicity | lyme disease treatment testimonial
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Use Brain (PET) Scans To Determine Diagnosis & Best Possible Treatment Options

Our research has proven that Chronic Lyme Disease patients suffer from a combination of Mold Toxicity and Industrial Toxicity. Mold Mycotoxins and Industrial Toxins reduce the “kill power” of the immune system via multiple mechanisms.

These toxins have been proven to have the following impacts on the body:

  • Inhibit bone marrow production of natural killer cells
  • Destroy TNF alpha, the primary “messenger” of the immune system
  • Destroy the Peyer’s Patch, the antibody factory in our intestine
  • Reduce the brain’s electrical activity (our brain is the computer that “runs” our immune system)

Neuroimmunologists now emphasize that “the immune system is simply the tail-end of the neurological system.” Our brain is the computer that “runs” our neurological system. Therefore, our brain is responsible for activating our immune system. Our Chronic Lyme disease patients have proven this concept to be true.

When we reverse the toxin-induced reduction of Brain activity in our Chronic Lyme Disease patients, their sluggish immune system ”wakes up”. It begins to effectively kill Lyme spirochetes they could not kill for years. A healthy brain recognizes ‘foreign invaders” and actively stimulates the immune system to move into attack mode. Lyme Disease treatment is an extensive process of healing for patients.

When we utilize our intravenous neurological protocols to detoxify the brain of Chronic Lyme Disease patients, we dramatically increase their brain activity, as seen in Dennis’ before-and-after PET-Brain scans below (middle image).

Optimizing Brain Function Increases Immune Function

With Neuroimmunologists emphasizing that the immune system is simply the ”tail end” of the neurological system, it becomes apparent that we must first fix the suffering brain of Chronic Lyme patients to increase their immune function.

Brain chemicals called neurotransmitters are chemical messengers that modulate the electrical function in our brain and body. These neurotransmitters effectively control the up-regulation and down-regulation of our immune function. Chronic Lyme patients always suffer severe deficiencies and drastic imbalances in their neurotransmitters. The more antibiotic therapy they have received, the more severe the distortion of brain chemistry and, subsequently, brain dysfunction.

Dr. Sponaugle’s research on how antibiotic therapy down-regulates brain function by changing brain chemistry began in 2006 and has been proven in thousands of patients. Dr. Sponaugle’s expertise allows far more effective treatment of Lyme-induced depression, brain fog, chronic fatigue, insomnia, anxiety, and panic disorders.

Detoxifying Environmental Toxins Increases Immune Function

Our clinical research has proven that many environmental toxins, including industrial toxins like Toluene and the black mold toxin Trichothecene, cause more global immune suppression than the Lyme toxin.

The toxin produced by the Lyme bacterium suppresses the production of a specific white blood cell, the CD 57 Lymphocyte. However, German research has proven that the Trichthecene T2 mold toxin suppresses both the humoral [antibodies] and cellular components of the immune system. Furthermore, German research has proven that Trichothecene destroys 1NF-alpha, the immune system’s primary messenger.

Trichothecene also inhibits RNA/DNA replication affecting om fastest-growing cells the most. Trichothecene toxicity at high levels causes leucopenia because bone marrow production of the white blood cells has a turnover of 120 days. Trichothecene and industrial toxins like Benzene reduce the production of all killer cells, not simply the CD 57 killer cells like the Lyme toxin. We have diagnosed severe Trichothecene toxicity in a majority of our “Chronic Lyme” patients, patients who have previously endured years of failed Lyme Treatment because of environmental toxicity.

Our Intensive Intravenous Treatment for Chronic Lyme Disease

Our chronic Lyme disease treatment protocols begin with healing detox IV therapy treatments to pull out toxins before moving into the “killing” phase.

Lyme disease treatment begins with up-regulating your natural immune system so that you can increase your body’s natural immune system “kill” power. These healing IV therapy treatments optimize the endocrine system and replace nutritional deficiencies from Gastrointestinal system dysfunction and leaky gut syndrome. These Detoxification infusions optimize your immune system's” killing power” and clear Mold toxins, Industrial toxins out of your body.

Once the healing IV therapy treatment is accomplished, you start the Lyme Kill Protocol. “kill protocol” IV therapy infusion treatments busting Biofilm, effectively treating the many diagnosed and diagnosed infections that Chronic Lyme disease patients suffer from.

Most of our Chronic Lyme treatment patients suffer from the following infections; Bartonella, Protomyxzoa, Mycoplasma, and sometimes Rocky Mountain Spotted Fever. Each patient has a different level of cumulative toxicity, infection, or parasite, as well as a different level of generalized sickness. So when we talk about a timeline for treatment, all of these factors must be considered.

Treatment for neurological lyme disease - eric
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Brenda watson pbs interviews dr. Sponaugle
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What Makes Our Approach to Lyme Disease Different?

Dr. Sponaugle designs an individual treatment plan for every patient suffering from Lyme disease. The standard medical treatment of Antibiotics for Lyme Disease is highly effective when the disease is diagnosed and caught early.

Dr. Sponaugle specializes in treating Chronic Lyme disease in which standard medical Lyme disease treatment has failed. No two Chronic Lyme patients suffer from the same extent of Lyme-induced brain damage or neurological impairment.

Thousands of Success Stories

With almost 10,000 successful recoveries from over 25 countries worldwide, we succeed where others have failed.

We Treat the Cause, Not Just the Symptoms

At Sponaugle Wellness Institute we use PET scans to create a precise diagnosis and individualized treatment plan.

Co-infections are Prevalent in Lyme Disease Sufferers

A weakened neurological system often leads to co-infections causing a multitude of debilitating symptoms.

Treatment All Under One Roof

Diagnosis, treatment and even family accommodations all happen in our beautiful medical clinic.

Chronic Lyme Disease is an immune-suppressing infection. Long-term immune suppression from Chronic Lyme Disease opens that gateway for multiple co-infections of every type of viral, bacterial, fungal, and parasitic. Lyme spirochetes, Bartonella, and the mosquito parasite, Protomyxzoa Rheumatica, will wrap themselves in biofilm if they are not immediately destroyed upon entry into our bloodstream. Biofilm is a protective shield manufactured by invading organisms to escape attacks from our antibodies, natural killer cells, and antibiotics.

Effective Chronic Lyme Disease Treatment requires a deep understanding of the Lyme Spirochete and tickborne infections like Bartonella and Babesia infections that live inside the cells of every organ in the body. Causing chronic illness and chronic Lyme disease symptoms throughout the entire body. Treatment for chronic Lyme disease requires much more than knowledge of microorganisms, antibiotics, and the immune system. Effective Chronic Lyme disease treatment requires additional expertise in the brain, and functions of multiple body systems including the endocrine system, gastrointestinal, and cardiovascular systems.

During your initial treatment, we perform a comprehensive evaluation to determine how well your brain and various body systems are functioning and specialized DNA testing to determine genetic antibody deficiencies that predispose you to a compromised immune system. This extensive consultation evaluates your immune system and neurological system, including an extensive analysis of brain chemistry and brain function, your gastrointestinal system and endocrine system, the entire hypothalamic system, and your pituitary adrenal (a gonadal axis with emphasis on pituitary [brain] hormones and specific hormones that are required for activation of the immune system). Immune function or “kill power is dependent on every organ in your body, therefore we analyze over 500 numerical biomarkers from various body systems.

From this analysis Dr. Sponaugle determines the complete causation of sickness, to better prioritize and design your individual treatment. Our testing will reveal if you have any additional stealth infections such as Babesiosis, Bartonellosis, or Protomyxzoa Rhuematica that are also destroying your mental and physical health. Our treatment is designed so you will receive the benefit of being treated for Lyme, while at the same time receiving a whole-body wellness protocol.

Wellness treatment is centered around clearing toxins, and optimizing your endocrine system, gastrointestinal system, and cardiovascular system resulting in optimized immune function. Hormonal deficiencies will be corrected to enhance neurotransmitter receptivity and subsequently the brain’s ability to “turn on” the immune system. Special emphasis is placed on pituitary brain hormones and downstream hormones that German research has proven are responsible for activating specific cytokines, cytokines are chemical messengers that activate your natural killer cells and regulate your overall “kill  power.”

Case Study: Excess Antibiotics for Chronic Lyme Disease

Carol received lyme disease treatment at the sponaugle wellness institute in oldsmar, fl.
Carol - Before Treatment
Carol from new jersey lyme disease treatment testimonial
Carol - After Treatment

Patient: Carol from New Jersey

Background: Prior to finding Sponaugle Wellness Institute, Carol was treated for six years by the best and brightest LLMDs in New Jersey and New York. Over that six-year period, she was prescribed multiple antibiotics. Most significant is the fact that she was prescribed four grams a day of IV Rocephin for a total of three years. Unfortunately, the Rocephin was ineffective in killing the massive Bartonella infection seen within biofilm formation* on her blood smear.

Diagnoses: Lyme Disease, Bartonella, Mold Toxicity, Industrial Toxins

Symptoms: Chronic Fatigue (Bedridden), Brain Fog, Anxiety, Insomnia, Depression, Malnutrition

Teaching Point: Carol was the first patient in which Dr. Sponaugle was able to determine that Mold Toxins and Industrial Toxins are sequestered in Biofilm formations. Excessive antibiotics are not effective for Lyme Disease patients who have biofilm saturated with lipophilic Mold and Industrial Toxins that suppress the immune system and natural kill power of the body to fight off infection and disease.

Biofilm eradication protocol for lyme disease
Biofilm Test for Carol
Biofilm buster treatment testimonial

The last three years of excessive antibiotic treatment rendered Carol essentially bedridden.

Carol’s story is a good case study for the concept that antibiotics are ineffective, if not worthless, in Lyme patients who have developed significant biofilm. Carol and her husband are one of the nicest couples I have met through 30 years of practicing medicine.

“Carol’s Lyme Disease Treatment made her worse than the Lyme Disease infection itself, much like my daughter, Alexa, who had the same experience in her treatment,” said Dr. Sponaugle. “Our Lyme disease treatment in 2012 was not nearly as advanced as it is in 2016, and I credit Carol’s amazing transformation – in just three months* – to the fact that she is truly a Christian woman who sincerely prayed for, and believed in her recovery.”

“Because Carol’s husband was a brilliant mathematician, he wanted, like me, to prove or disprove concepts with numerical data, not guesswork,” said Dr. Sponaugle. “Therefore he allowed me to perform testing precisely before and immediately after we used our “biofilm-busting” IV Infusions.”

“To prove many of my theories through clinical research, we have had to eliminate variables, perform biomarker testing with precise before-and-after time frames, and use deductive reasoning. Patients remain the best teachers if we pay attention,” Dr. Sponaugle said.

“Over that six-year period, she was prescribed multiple antibiotics. Most significant is the fact that she was prescribed four grams of IV Rocephin daily for three years. Unfortunately, the Rocephin was ineffective in killing the massive Bartonella infection.”



Lyme Disease is most commonly spread by the bite from a blacklegged or deer tick. These tiny ticks and tick bites are very small and difficult to see.


A relative of the STD Syphillis, our research has shown Lyme Spirochetes can be transmitted by sexual intercourse.

Sexually Transmitted

A relative of the STD Syphillis, our research has shown Lyme Spirochetes can be transmitted by sexual intercourse.

Lyme Disease Treatment Testimonials

Take a moment to watch these amazing stories of healing and know that we are always ready and eager to make a difference in your life or the life of a loved one who may be dealing with chronic Lyme disease or neurological symptoms of Lyme disease.

Lyme Disease Treatment

Mauryah and mia - lyme disease patients at sponaugle wellness institute

At Sponaugle Wellness Institute, we have successfully treated Chronic Lyme Disease patients from around the world. The majority of our Lyme Disease patients have previously undergone treatment by 20 or more physicians.

Mauryah from Canada (at right) arrived at our clinic in a wheelchair due to dizziness and pain. In 16 weeks of Dr. Sponaugle’s integrative Lyme Disease treatment, her brain was clear and she was again running and exercising as she had in high school.

Mia from Australia underwent treatment of Lyme Disease at Sponaugle Wellness Institute and was out of her wheelchair in 12 weeks. She returned to Australia without her wheelchair and continued residual treatment for Lyme disease.

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