Lyme Disease Treatment
The majority of our Lyme Disease patients have previously undergone treatment by 20 or more physicians.

At Sponaugle Wellness Institute, we have successfully treated Chronic Lyme Disease patients from around the world.  Vastly misunderstood, Lyme Disease symptoms mimic those of other diseases making it commonly misdiagnosed as something else. Symptoms of Lyme Disease are extremely severe and debilitating, leaving sufferers feeling like it has stolen their lives. The Sponaugle Wellness team of doctors have dedicated their lives to understanding and successfully treating Chronic Lyme Disease.

Successful Treatment for Lyme Disease

Thousands of Success Stories

With almost 10,000 successful recoveries from over 25 countries worldwide, we succeed where others have failed.

We Treat the Cause, Not Just the Symptoms

At Sponaugle Wellness Institute we use PET scans to create a precise diagnosis and individualized treatment plan.

Co-infections are Prevalent in Lyme Disease Sufferers

A weakened neurological system often leads to co-infections causing a multitude of debilitating symptoms.

Treatment All Under One Roof

Diagnosis, treatment and even family accommodations all happen in our beautiful medical clinic.

Patient Success Stories

Patients from all over the world, many confined to wheelchairs, regaining their health and their life. These are their real stories.

Lyme Disease is often misdiagnosed. Are you experiencing any Lyme Disease symptoms?

  • Tick Bite or Mosquito Bite

  • EM (Erythema Migrans) Rash

  • Severe Headaches or Neck Stiffness

  • Joint Pain or Swelling including Arthritis

  • Facial Palsy or Loss of Facial Muscle Use

  • Dizziness or Shortness of Breath

  • Nerve Pain, Numbness, Tingling or Shooting Pain

  • Intermittent Pain in Bones, Joints, Tendons or Muscles

  • Short Term Memory Loss

Still Have Questions?

We’d love to talk.
yonanda lyme disease

Yolanda Hadid's Lyme Story & Treatment at Sponaugle Wellness Institute

Real Housewives star Yolanda Hadid (Yolanda Foster) received treatment at Sponaugle Wellness Institute for Lyme Disease. She opens up about it in her new book, “Believe Me.”

Suzanne Somers Recommends Sponaugle Wellness Institute

Suzanne Somer’s interviews her granddaughter Violet about her struggle with Lyme and her successful treatment at Sponaugle Wellness Institute



Lyme Disease is most commonly spread by the bite from a blacklegged or deer tick. These tiny ticks and tick bites are very small and difficult to see.


New evidence has found Borreliae detected in mosquitos. This is what causes Lyme Disease in humans, spread from ticks.

Sexually Transmitted

A relative of the STD Syphillis, our research has shown Lyme Spirochetes can be transmitted by sexual intercourse.

What Makes Treatment At Sponaugle Wellness So Successful?

Holistic Treatment Backed by Science. In short, we use brain (PET) scans to determine diagnosis and best possible treatment options.

Our research has proven that Chronic Lyme Disease patients suffer from a combination of Mold Toxicity and Industrial Toxicity. Mold Mycotoxins and Industrial Toxins reduce the “kill power” of the immune system via multiple mechanisms. These toxins:

  • Inhibit bone marrow production of natural killer cells
  • Destroy TNF alpha, the primary “messenger” of the immune system
  • Destroy the Peyer’s Patch, the antibody factory in our intestine
  • Reduce the brain’s electrical activity (our brain is the computer that “runs” our immune system).

Neuroimmunologists are now emphasizing that “the immune system is simply the tail-end of the neurological system.” Our brain is the computer that “runs” our neurological system, therefore our brain is responsible for activating our immune system. Our Chronic Lyme disease patients have proven this concept to be true*.

When we medically reverse the toxin-induced reduction of brain activity in our chronic Lyme disease patients, their sluggish immune system ”wakes up” and begins to effectively kill Lyme spirochetes they were unable to kill for years*. A healthy brain recognizes ‘foreign invaders” and actively stimulates the immune system to move into attack mode.

When we utilize our intravenous neurological protocols to detoxify the brain of Lyme disease patients, we dramatically increase their brain activity leading to healing from the source.

lyme pet scan


In worldwide MRI studies on patients who tested positive for Borrelia, antibodies in their spinal fluid have proven that spirochetes – which is the corkscrew-shaped bacterium causing Lyme Disease (called Borrelia Burgdorferi) – have a propensity to attack three regions of the brain (which modulate motor function):

1. The Sensory Motor Strip
2. The Cerebellum
3. The Basal Ganglia

The Basal Ganglia includes the three motor regions that control involuntary movement:

1. The Caudate Nucleus
2. The Lentiform Nucleus
3. The Substantia Nigra (known as the Parkinson’s region).

The doctors at Sponaugle Wellness Institute use PET-brain imaging to obtain more sophisticated data of these regions for treatment. Additionally, our PET-scan database now catalogs hundreds of Lyme Disease patients, allowing us to continuously improve treatment for the benefit of others.

Through computerized calculation, PET scans provide numbers for more objective evaluation of brain activity. The PET-scan computer calculates glucose metabolism by brain region, and glucose metabolism correlates with electrical activity.

Our preference for treating Lyme Disease is to reduce the brain’s toxin load to ground zero, before commencing to kill protocols in Neurological Lyme Disease patients.

However, because effective killing of Lyme spirochetes, Bartonella, Protomyxzoa and other infectious organisms releases lipopolysaccharide (LPS) toxins from their cell walls, the brain becomes temporarily more toxic during treatment.

We address this as part of treatment by clearing this toxic effect during brain-scans, making it easier to evaluate and treat the brain regions that are under-active due to infection.

Understanding Biofilm in Connection with Lyme Disease

Biofilm is a protective shield manufactured by invading organisms to escape attack from our antibodies and natural killer cells of our immune system.

Biofilm consists of a polysaccharide extracellular matrix described by microbiologists as a “super glue-like” substance.

Lyme spirochetes, Bartonella, and the mosquito parasite, Protomyxzoa Rheumatica, will wrap themselves in Biofilm if they are not immediately destroyed upon entry into our bloodstream. Thinking in three-dimensional terms, visualize Biofilm “bubbles” floating among red blood cells throughout the bloodstream, as seen in this blood smear (left).

Biofilm formations – serve as a protective shield for Lyme spirochetes, co-infections, parasites and viral infections (like Epstein Barr). The image on left shows Biofilm; the image on right shows no Biofilm.

Lyme Disease Symptoms

Lyme Disease and Co-Infections

Many patients suffer chronic infections because their toxin-induced immune system isn’t strong enough to destroy Biofilm. When we use integrative medicine protocols to restore immune function in Chronic Lyme Disease patients, their immune system properly attacks and destroys Biofilm formations in the bloodstream. Patients will then test positive for multiple undiagnosed Bacterial, Parasitic and Viral infections that were previously hidden in Biofilm*.

Infectious organisms are then released to the free floating-bloodstream. Most commonly diagnosed, in addition to Borrelia Burgdorferi (typically the cause of Lyme Disease), are the following:

  • Babesia

  • Bartonella

  • Borrelia Miyamotoi (CA patients)

  • Brucellosis

  • Chlamydia Pneumoniae

  • Chaga’s Disease

  • Mycoplasma Pneumoniae

  • Protomyxzoa Rheumatica

  • Rocky Mountain Spotted Fever

  • Toxoplasmosis

  • Tularemia

  • West Nile Virus

Lyme Disease Linked with Gut Toxicity

We have correlated abnormal brain chemistry patterns with Lyme bio-marker CD 57 levels and the abnormalities seen on the brain scans of our Lyme patients. Our Chronic Lyme disease research has proven that antibiotic-induced changes in brain chemistry cause excessive electrical activity in two specific brain regions
gut toxicity brain
When these brain regions become severely overactive, patients develop depression and a “worry-worry” type of anxiety. When Chronic Lyme disease patients develop an overactive deep limbic center, they suffer with depression, moodiness, negativity, irritability, hopelessness, excessive guilt, social anxiety, and they become more easily offended. When Chronic Lyme Disease patients develop an overactive anterior cingulate, they become more argumentative, more stubborn, hyper focused on the negative, and they develop obsessive-compulsive worry*.


Patients who have an overactive deep limbic center often suffer from...



Patients who have an overactive anterior cingulate often suffer from...


Antibiotic-Induced Gut Toxicity Suppresses Immune Function

Lyme disease patients often become more debilitated after months of aggressive antibiotic therapy. Furthermore, prolonged antibiotic therapy suppresses the immune system in Chronic Lyme disease patients. Lyme disease treatment consisting solely of antibiotic therapy can ultimately destroy the intestinal lining (where 70 percent of our immune system is located). Intestinal dysbiosis is the term used to describe an imbalance of intestinal organisms.

Prolonged antibiotic therapy ultimately kills our good intestinal bacteria. Lactobacillus is a healthy intestinal bacterium that produces lactic acid. Lactobacillis thereby ensures that the ph of our intestine remains more acidic disallowing overgrowth of foreign invaders. After prolonged antibiotic therapy, the intestinal ph becomes more alkaline allowing excessive overgrowth of pathogenic yeast and the following toxic bacterium: Klebsiella, Proteus, and Enterobacteriaceae. When Candida mycotoxins and bacterial endotoxins destroy the intestinal lining they also destroy our antibody factory, the Peyer’s patch which is located in our intestinal lining.

Destruction of the intestinal lining also causes severe malnutrition. Several of the essential amino acids are utilized to make natural killer cells. Thus production of killer lymphocytes suffers from a malnourished state. With enough antibiotic-induced destruction of the intestinal lining, Lyme disease patients develop severe Leaky Gut Syndrome. Once Lyme patients develop significant Leaky Gut Syndrome, their Immune System will waste resources attacking undigested food particles that “leak” across the damaged intestinal lining into the blood stream. Normally, these food particles are too large to cross over from the gut into the bloodstream.

Antibiotic-Induced Gut Toxicity Causes Increased Brain Toxicity

After Chronic Lyme disease patients develop antibiotic-induced gut toxicity, yeast mycotoxins and bacterial endotoxins migrate from the gut to the brain. These toxins are fatty in structure and deposit in the fattiest organ, our brain which is 60 percent fat. These neurotoxins inflame the brain’s white matter, the insulation on brain neurons called myelin, adding to the cumulative level of neurotoxicity which is already significant from an accumulation of Lyme toxins in Lyme patients.

Antibiotic-induced neurotoxicity causes further suppression of the immune system by “shutting down” the electrical current in the brain. This is problematic, because the brain’s electrical activity is responsible for stimulating cytokine activity. Cytokines are the chemical messengers that activate our natural killer cells. When neurotoxins inflame the myelin sheath of brain neurons, they change the electromagnetic field surrounding the neuron; slowing the speed of the electrical impulse. By this mechanism, neurotoxins essentially suppress the brain’s electrical activity. In a healthy brain, electrical current jumps over the myelin on brain neurons in rapid fashion. However, when the myelin sheath becomes infiltrated with fatty neurotoxins from the gut, in addition to toxins from the Lyme disease spirochete, it fails to effectively modulate immune function.

antibiotic mylan damage
dr sponaugle
Meet the Medical Director of Sponaugle Wellness Institute


With emphasis on Environmental Medicine, Dr. Sponaugle specializes in treating brain and neurological disorders derived from Neurological Lyme disease, Mold Toxicity, Industrial Toxicity, Gut Toxicity, and more. Dr. Sponaugle approaches healing on an intracellular level using biochemistry and detoxification protocols to optimize mitochondrial function.

From his beginnings in the 1980’s practicing Critical Care Medicine and Anesthesiology Dr. Sponaugle felt there was a better way to heal his patients. He began Sponaugle Wellness and has helped thousands of people get better. Dr. Sponaugle has gained national acclaim for his work including being invited to the white house, celebrity collaborations and treatments, publications and numerous television appearances.