SOT for Lyme Disease

SOT Therapy for Lyme Disease & Co-Infections

 

SOT Therapy for Lyme Disease

SOT therapy is a groundbreaking treatment for chronic infections, including the bacteria causing Lyme disease and associated co-infections. Due to the complexity of how these infections can hide from the human immune system, essentially a chronic persisting disease, SOT is a way of educating our cells to be more efficient at finding them.

Essentially SOT creates a shutoff “key” fitting a “lock” portion of a pathogen. The “lock” is a specific section of DNA controlling an important function of the pathogen. The “key” binds to the “lock,” thus blocking this function. This prevents the bacteria from making essential proteins, essentially shutting off bacterial replication. Unable to replicate, the bacteria are unable to cause disease.

Whereas most therapies have a short half-life like antibiotics or herbals, the SOT compound continues to travel to several specific microbial targets, fighting the infection 24/7 for three to six months.

What is Supportive Oligonucleotide Technique (SOT Therapy)?

Supportive Oligonucleotide Technique (SOT) is a new revolutionary treatment for Cancer, a host of viruses, Lyme bacterial infections, and co-infections.

Each SOT is tailored to a patient's cancer, virus, or infection and works by creating a shutoff "key" that fits into a chosen "lock" portion of a pathogen or cancer cell.

The “lock” is a specific section of DNA that normally controls an important function of the cancer cell or pathogen.

The “key” binds to the “lock” and blocks the function and the replication of the cell – thereby killing the cancer cell or pathogen and preventing its replication.

If a patient has multiple active infections, multiple SOT treatments will be needed for each infection.

Through the replication of genes and then the creation of an antisense copy, the abnormal genes are silenced.  In the laboratory, 500 million-1 billion copies of the unique SOT molecule are formulated.

SOT therapy is a groundbreaking treatment for chronic infections, including the bacteria causing Lyme disease and associated co-infections. Due to the complexity of how these infections can hide from the human immune system, essentially a chronic persisting disease, SOT is a way of educating our cells to be more efficient at finding them.

Whereas most therapies have a short half-life like such as antibiotics or herbals, the SOT compound continues to travel to several specific microbial targets, fighting the infection 24/7 for three to six months.

SOT and Antisense Oligonucleotides

Nucleotides are the molecules that form the backbone of our DNA.  Oligo means “few” or “small.”  Oligonucleotides are short single-strand DNA molecules.  The creation of a specific oligonucleotide intended to bind to its counterpart in the body is called an “antisense” oligonucleotide.  Antisense implies the mirror image or the “lock and key” analogy.

The SOT is a small oligonucleotide that is complementary to a specific sequence of each gene which is related to the most active target options inside the cancer cell, viruses, or Lyme bacteria (e.g., acylguanidines, RNA, non-nucleoside transcriptase, etc.).  This is based on each individual and the most active target for that individual.

The SOT life span is increased by a proprietary technology that makes this molecule unrecognizable by the enzymes that normally break down oligonucleotides and, at the same time, helps the SOT keep the same solubility feature membrane penetration and other complementary hallmarks as the normal oligonucleotides.

Hence, the SOT has a potent ability to block a specific target and at a very high rate, the expression and transcription of a gene that encodes a protein with one of the target options used. Since the molecule is not degraded, the complementary mRNA then releases the SOT to move on to the next target with the same sequence. Hence, one molecule of SOT can potentially block many other relative targets in a very specific way. Therefore, death can be re-engaged in cancer cells, viruses, and Lyme bacteria.

Finally, since it is complementary to one of the target options inside cancer cells, viruses, and Lyme bacteria, it is highly specific to these only. It will only work for the patient that it was made for.  The SOT rarely causes adverse reactions since it is highly compatible with the organism.

Sot therapy for lyme disease
SOT Therapy Mechanism of Action for Lyme Disease

SOT for Lyme Disease & Tickborne Coinfections

SOT treatment consists of tiny oligonucleotides that “match” the precise sequence of particular genes of the Lyme bacterium species, co-infection bacteria, or virus we attempt to eradicate.

SOT therapy is always looking for the Lyme species or virus to target. Lyme bacteria and viruses send out signals to multiply themselves regularly. Because the SOT molecules block that communication and force the bacterium or virus cells to self-destruct, the Lyme bacteria or virus we’re treating dies. It operates 24 hours a day, seven days a week, and does not lose effectiveness over (up to) six months. As a result, we can “switch off” the Lyme illness, Lyme co-infections, and viral replication cycle.

SOT is now available for many viral infections, including Epstein-Barr, CMV, herpes, HHV-6, HIV, hepatitis, HPV, and others, and Lyme, Ehrlichia, Babesia, and Bartonella.  Once administered, the SOT works by inhibiting gene replication to these infections.

Sot therapy for lyme disease
SOT Therapy for Lyme Disease

The figure shows an example of a pathogen such as the Lyme bacteria. Inside the cell nucleus (yellow), bacterial DNA is used to transcribe messenger RNA (mRNA). The mRNA is sent out of the nucleus into the main part of the cell, the cytoplasm. There, mRNA joins amino acids into proteins essential for various bacterial activities, including reproduction.

SOT therapy works by creating a short segment of complementary DNA in the lab that binds to the specific mRNA segments and prevents the bacteria from making essential proteins, essentially shutting off bacterial replication. Unable to replicate, the bacteria are unable to cause disease.

SOT therapy is not a drug in the traditional sense. It is not an antibiotic, nor is it gene therapy. It does not change the genetic structure. There is no gene splicing, gene insertion, or manipulation. SOT therapy is a stealth technology with small molecules that can avoid detection and destruction by the immune system or RNA degrading enzymes for months, allowing them to quietly circulate through the body, attaching to their viral or bacterial targets.

SOT Therapy Frequently Asked Questions

What diagnostic tests are used for SOT therapy?

We use a variety of testing to determine whether you are a possible candidate for SOT therapy. You must have a positive lab result for a particular infection within the last six months.

How Does SOT Therapy Work?

SOT therapy utilizes molecular building blocks (mRNA) found naturally in the patient’s body. Nucleotides are the molecules that form the structure of DNA and RNA.

SOT therapy creates an oligonucleotide complementary to a specific sequence for each gene. It is designed to bind to this gene’s counterpart (mirror image) in the body, thus blocking its function. It blocks a specific target at a very high rate – stopping the expression and transcription of a specific gene. SOT terminates gene replication sequences, thus eradicating pathogens or cancerous cells from the body and preventing future lifecycles of these cells.

What are the side effects of SOT Therapy?

As the SOT is derived from the patient’s blood, the side effects are usually minimal. The main side effects of SOT treatment are detox or “Herx” reactions, such as fatigue, body aches, fever, and headache. Patients who have gone through treatment often say, “your symptoms get worse before they get better.”

The SOT may be repeated up to 3x per year if needed. With each round of SOT, retesting for the presence of pathogens is recommended. At some point, the infection may be completely eradicated or remain stable in quiet remission.

What kind of viruses can be treated with SOT THERAPY?

  • Herpes Simplex Virus (HSV) 1 and 2,
  • Varicella Zoster Virus (VZV),
  • Epstein-Barr Virus (EBV),
  • Human Papilloma Virus (HPV) 16/18,
  • HTLV1, Hepatitis B Virus,
  • Hepatitis C Virus,
  • Human Immunodeficiency Virus (HIV),
  • Coxsackie Virus Type A & B.

How Do You Know If the SOT Therapy Was Successful?

Clinical & Laboratory findings improve. This would require a discussion with your treating clinician.

What is the process for receiving SOT Therapy?

After confirmation of infection is established, the patient’s blood is drawn to obtain circulating Lyme bacteria or viruses. The blood is sent to RGCC laboratory in Greece. RGCC lab identifies the main genetic sequence of the target replication genes for the organism, then creates a complementary oligonucleotide (short nucleic acid) sequence to block replication. It takes about four weeks to create a SOT.

When completed, the RGCC ships the SOT back to the clinic, where it is then infused intravenously and administered to the patient for about an hour. Intravenous antihistamines and low-dose steroids are given immediately before SOT administration to lessen the already rare chance of an allergic reaction and tighten the vein walls to minimize the leaking of SOT.

How often should patients carry out a follow-up test?

It depends on the treatment plan provided by your clinician.

Are there any contraindications to the SOT Therapy?

  • Pregnancy or breastfeeding
  • Recent blood transfusion – Please allow a safety period of 120 days
  • Recent cytotoxic chemotherapy and/or radiotherapy. Please allow a drug-free window of 2 weeks before the application
  • Children under the age of 4 for viral or Lyme

 

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